Patent Expiry of Blockbuster Drugs for Treatment of Kaposi Sarcoma to Present Lucrative Opportunities

The global Kaposi sarcoma (KS) market is immensely consolidated and the top two players, namely Johnson & Johnson and Merck & Co. Inc. accounted for almost 50% of the overall market in 2015. The contribution of domestic players such as Sun Pharmaceutical Industries Limited is presented low. However, Transparency Market Research predicts that the contribution of these companies will increase during the forecast period owing to the patent expiry of several major drugs.

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Partnerships, acquisitions, and collaborations with other leading companies for the development of newer products with improved efficacy are part of the growth strategies adopted by a number of players in the Kaposi sarcoma market. For instance, F. Hoffmann-La Roche Ltd launched a new Global Access Program in September 2014 in partnership with the Joint United Nations Program on HIV/AIDS, the President’s Emergency Plan for AIDS Relief, the Clinton Health Access Initiative, and the Global Fund. The program was centered on HIV viral load testing.

High Incidence of HIV/AIDS, Organ Transplants Driving Growth of KS Market 

Increased organ transplant procedures are a leading factor driving the Kaposi sarcoma market since the incidence of the cancer is high among patients who have undergone an organ transplant. “Organ transplant patients are given immunosuppressive agents to prevent their body from rejecting the graft. This makes them highly susceptible to Kaposi sarcoma associated herpesvirus (KSHV) infection,” the author of the study explains. The long term use of these agents increases the rate of risk of these patients by more than 100 times compared to the general population.

The high incidence of HIV/AIDS associated Kaposi sarcoma is one of the major factors driving the adoption of HAART therapy, which subsequently fuels the overall KS market.

High Cost of Treatment a Major Drawback 

The cost of cancer drugs used for the treatment of Kaposi sarcoma has been on the rise in the past few years, making it difficult for patients to seek treatment. This is a major concern for both the patients and the payers. “The prices of patented drugs have increased by over five times in the past few years in the U.S. and continue to rise,” the TMR analyst comments. For instance, prices of major drugs used for the treatment of KS, such as liposomal doxorubicin, liposomal daunorubicin, or paclitaxel in combination with HAART, have been increasing significantly, making these unaffordable for middle and lower income groups.

Slow but Steady Growth in Store for Kaposi Sarcoma Market 

The global market for Kaposi sarcoma is projected to expand at a modest 2.2% CAGR from 2016 to 2024, with the opportunity in the market rising from US$118.5 mn in 2015 to be worth US$143.2 mn by the end of the forecast period. Hospitals formed the leading distribution channel in 2015, generating over US$40 mn revenue that year. The segment is also slated emerge as the fastest growing segment in the KS market, expanding at a 2.6% CAGR from 2016 to 2024.

By type of treatment, HAART led the overall Kaposi sarcoma market in terms of revenue, with chemotherapy and immunotherapy poised to register the highest growth rate over the coming years. In terms of region, the global Kaposi sarcoma market was led by North America in 2015 and the MEA region will record the fastest growth by 2024.

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Organ Transplantation Procedures Fuel the Kaposi Sarcoma Market

Kaposi Sarcoma (KS) is type of cancer that originates from cells lining blood vessels and lymph nodes. This cancer mainly occurs in the form of tumors on mucous lined surfaces or also on skin. However, Kaposi Sarcoma might also form in other body parts such as the lungs and digestive tracts. The cancerous cells might form purple, brown, or red patches on skin, which are called lesions.

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How is the global Kaposi Sarcoma market’s vendor landscape?

This market mainly depicts a consolidated competitive landscape, wherein only two players jointly held nearly half of the total market shares in 2015. Johnson & Johnson and Merck & Co. Inc. are these two companies which have dominated the vendor scenario in the global Kaposi Sarcoma market. In spite of this, other players are also expected to experience higher contribution towards betterment of the market in future, especially after patents of key drugs sold by the bigwigs expire.

Most of the competitors have embraced strategies such as collaborations, acquisitions, and partnerships for improving their stance in this market.

Which Factors extensively drive the global Kaposi Sarcoma market?

Organ transplantation procedures have seen a rapid rise in the last few years, and this is a key factor driving the market. This is mainly due to higher chances for cancer to exist among patients who have went through an organ transplantation. Most patients about to go through organ transplantation are given immunosuppressive agents that make their body readily accept the transplantation graft. However, doing this increases the risk of patients to catch the cancer. High incidence of HIV/AIDS especially in emerging economies also is prominent factor driving the global Kaposi Sarcoma market.

What is the most prominent drawback of the global sarcoma market?

Extensively high costs of cancer drugs is a prime restraint affecting the market, which might discourage people from opting for necessary treatment. Price of patented drugs also have skyrocketed, making it difficult for middle-class people to seek out treatment. However, several governmental bodies are putting forth initiatives such as funding and reimbursement programs, which could change the entire picture.

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