Cancer is a life taking disease that has taken many lives worldwide. Since many years, researchers have been trying to find ways to treat cancer by developing various drugs, treatments, and medicines. In a recent study, researchers from the University of Missouri have unraveled the position of the cancer-critical enzyme on the cell surface. The enzyme allows tumor cells to make a way through collagen. This creates a convenient path for the tumor to spread cancer all over the body. This result will widely help pharmaceuticals to prevent and treat the spreading of cancer in the body.
Collagen a Critical Protein that Carries Tumor Cells
Tumor cells make their way through collagen to spread cancer. Collagen is the most abundant protein present in the human body that provides structural strength to spread cancer to tissue and bones. In this, scientists have found one enzyme called MT1-MMP. This enzyme sits on the surface of a tumor cell and digests the collagen in its path. It further makes a pathway for tumor cells to spread. The study that suggests it can be possible to interrupt the way enzyme sits on the tumor cells. This will potentially block the ability of the enzyme to digest collagen and obstruct the spread of cancer.
Decades ago, scientists have studied metalloproteinases, a class of this enzyme, but the focus was too broad. The study failed and these enzymes were neglected. On the other hand, the current study specifically focused on the MT1-MMP enzyme that helped them to gather specific results. It will further help in drawing particular applications for potential pharmaceuticals and further research.