According to medical interpretation, multiple sclerosis attacks the central nervous system, and over a period of time cause loss of balance and muscle tremors. A new gene, Gsta4 identified by researchers at Karolinska Institutet protects a certain kind of cell in the brain from being destroyed. Following this research, published in Nature Communications, researchers opine significant improvement in the treatment of this serious disease.
“Collectively, the findings are particularly interesting for several reasons,” said the corresponding author of the study. So far, no much is not known about the progressive mechanism of multiple sclerosis, the phase of the diseases in which oligodendrocytes and neurons in the brain die without re-forming.
Meanwhile, brain neurons can be compared to electric wires. The cells that give such insulation are termed oligodendrocytes, and it is these cells that the immune system attack in the early phse of multiple sclerosis.
The possible mechanisms that influence how well oligodendrocytes advance into functional cells and their survival during this process studied by researchers at Karolinska Institutet.
Multiple Sclerosis lasts long, says medical knowledge
Clinically, multiple sclerosis is a disease of the central nervous system and can last for many years. In many cases, it leads to other problems including loss of sensation, difficulties walking, visual impairment, tremors, mood swings, and loss of sensation.
In the early stage of multiple sclerosis, oligodendrocytes are able to remake and mature into new insulating cells, thus repairing neuronal functionality in the patient. However, the function is gradually blocked and so is its ability of the protective, insulating cells to fully mature. Due to lack of scientific knowledge of this, currently there is no treatment available.