Opioid Induced Constipation Treatment Market: Players Vie to Introduce Novel Drugs to Serve Unmet Demand

There are multiple drugs in the pipeline for opioid induced constipation treatment. Upon approval, these drugs will face little competition in this market which is largely untapped. There have not been many stable choices in the pharmaceutical industry for opioid induced constipation treatment over the recent past, but the continuous approval rate of highly targeted drugs is expected to provide a strong push to this market’s growth rate. This includes the PAMORA drugs that help treat OIC without intervening in the opioid’s action on the patient.

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In a highly consolidated opioid induced constipation treatment market, the top three companies, namely Takeda, Boehringer Ingelheim, and Valeant Pharmaceuticals International Ltd collectively held 91.8% in the overall market in 2014. However, Takeda Pharmaceuticals Company Ltd enjoys clear dominance because of popularity of its approved drug Amitiza.

Innovation of novel drugs is the key growth strategy players in the opioid induced constipation treatment market have resorted to. This is to serve the demand for new drugs that are less likely to face competition in this largely untapped market. Savvy players are vying to tap into the opportunities that are brimming in this market.

According to a report by Transparency Market Research (TMR), the global opioid induced constipation treatment market is likely to rise at a whopping 31.2% CAGR vis-à-vis revenue for the forecast period between 2015 and 2023. This will translate the demand in the market into a revenue of US$4.81 bn by 2023-end considerably up from US$731.2 mn in 2016. While chloride channel activators stood as the leading drug class in the opioid induced constipation treatment in 2016, mu-opioid receptor antagonists are likely to overtake over the report’s forecast period. This is mainly because of approvals received by an increasing number of mu-opioid receptor antagonists and their higher efficacy over other drugs. Region-wise, North America is likely to continue to lead in the opioid induced constipation treatment market until 2023.

Large Number of Pipeline Drugs to Receive Approval to Benefit Market

Across the world, the number of individuals suffering from opioid induced constipation is on the rise. As per statistics of the American Academy of Pain Medicine, in 2013, almost 100 million patients in the U.S. were suffering from opioid induced constipation. The number is predicted to rise as the number of individuals consuming opioid drugs increases. In addition, rising awareness about the commercial availability of host of opioid drugs is also leading to their adoption for chronic pains.

Presently, there are several pipeline drugs for the treatment of opioid induced constipation. The approval of these drugs will foster the growth of this market which currently remains largely untapped. The choice of drugs for the treatment of opioid induced constipation has been shaky, but approval of highly targeted drugs is likely to provide impetus to this market’s growth. PAMORA class of drugs are in the pipeline to treat opioid induced constipation without interfering opioid’s action on the patient.

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