A research initiative at the Nanyang Technological University, Singapore has led to the development of an exemplar device. The device provides a faster and less invasive means to seal holes and perforations in blood vessels. It does so by using an electrical powered patch of glue applied using a minimally invasive balloon catheter.
The device could replace the need of keyhole surgery to stitch or patch up internal defects in blood vessels, opine the researchers.
In terms of its function, post insertion of the catheter into a suitable blood vessel, the glue patch can be directed to the site of the tear. Following this, it can be activated using retractable electrodes to seal it in a few minutes, without the need of even one surgical cut.
The device patented by the Massachusetts Institute of Technology and Nanyang Technological Institute is a new type of sealant that works in moist environments and toughen when voltage applied to it.
Meanwhile, the catheter that deploys the newly developed glue patch is developed jointly by a team of research associates at Nanyang Technological University and MIT.
In fact, the catheter is the first proof-of-concept application of the glue patch in a clinical environment since it was created in 2015.
The findings of the research is published in the scientific journal Science Advances.
The system of glue patch and catheter that is developed is potentially the answer to the current unmet need for a minimally invasive technique for blood vessel repairs. This includes repairs of arteriovenous fistulas and vascular leaks without the need of open surgery. Together with the system of the glue patch and the catheter, the possibility of eliminating surgical incisions to join something inside opens up.