Cell separation or isolation methods play crucial part in stem cell studies and several other biological applications. They also exhibit high potential in clinical settings. Over the years, a number of approaches in cell separation methods have been discovered by scientists. Their use in diverse applications is a key aspect of the evolution of the cell separation market. So diverse are the applications that not a single cell isolation method or technology can meet all the criteria, which include viability, activation status, frequency, and cell purity.
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Need for Platforms with High Throughput
Cell biologists seek cell separation approaches for transplantation of blood cells or mesenchymal stem cells (MSCs). Over the past few years, the growing clinical potential of regenerative therapies has added a big impetus to the adoption of new cell separation strategies. Emerging applications include oncology, underpinning the vast revenue streams for industry players in the cell separation market. A case in point is growing demand for CTC separation methods in breast cancer. To this end, regulatory agencies such as the U.S. FDA has also approved state-of-the-art cell separation platforms. Cell therapy research applications have attracted vast interest in developed world. Another area is in the management of chronic diseases, where they are used in hematotoxicity testing.
Need for meeting various downstream applications for the isolated cells has nudged cell biologists to use platforms with high efficiency and purity. This improves the rate of recovery of desired cells in downstream cell culture applications. Biotech companies and biopharma players in developing and developed countries are leveraging these technologies for emerging downstream bio-processing, such as protein research, surface protein expression.
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Some of the aspirants looking for sizable stakes in the cell separation market are Bio-Rad Laboratories, Inc., GE Healthcare, Merck KGaA, STEMCELL Technologies Inc., Beckman Coulter, Inc., and Thermo Fisher Scientific, Inc.